Home / GnRH Agonist / Goserelin acetate

Goserelin acetate

3592 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3592/10
Goserelin acetate
1 Image
Description: GnRH receptor agonist
Product Details
Supplemental Products
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Goserelin acetate is a synthetic gonadotropin-releasing hormone (GnRH) analog that behaves as an agonist at the GnRH receptors. Stimulates gonadotropin and sex hormone release in the short term, and causes suppression with continued administration. Displays antiproliferative activity in breast, prostate and endometrial cancers.

Technical Data

M.Wt:
1269.42
Formula:
C59H84N18O14
Sequence:
XHWSYSLRP

(Modifications: X = Pyr, Ser-4 = t-Bu-Ser, Pro-9 = terminal NH-NH-CO-NH2)

Solubility:
Soluble in water
Storage:
Desiccate at -20°C
CAS No:
145781-92-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Antiproliferative effects of luteinizing hormone-releasing hormone (LHRH) agonists on human androgen-independent prostate cancer cell line DU 145: evidence for an autocrine-inhibitory LHRH loop.
    Dondi et al.
    Cancer Res., 1994;54:4091
  2. The expression of gonadotropin-releasing hormone and its receptor in endometrial cancer, and its relevance as an autocrine growth factor.
    Chatzaki et al.
    Cancer Res., 1996;56:2059
  3. Goserelin. A review of its pharmacodynamic and pharmacokinetic properties, and clinical use in sex-hormone-related conditions.
    Chrisp and Goa
    Drugs, 1991;2:254

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

⚠ WARNING: This product can expose you to chemicals including Goserelin acetate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

FAQs

No product specific FAQs exist for this product, however you may

View all Peptide FAQs

VersaClone cDNA Plasmids

Human GnRHR (NP_000397) VersaClone cDNA

RDC0324

Mouse GnRHR (NP_034453) VersaClone cDNA

RDC0415

Rat GnRHR (NP_112300) VersaClone cDNA

RDC0611

Reviews for Goserelin acetate

There are currently no reviews for this product. Be the first to review Goserelin acetate and earn rewards!

Have you used Goserelin acetate?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.