GW 791343 hydrochloride

Tocris Bioscience | Catalog # 3385

Allosteric modulator of P2X7 receptors
Tocris Bioscience
Discontinued Product
3385 has been discontinued. View all P2X Receptor Modulators products.

Key Product Details

Description

Allosteric modulator of P2X7 receptors
View all P2X Receptor Modulators »

Product Description

GW 791343 hydrochloride is a P2X7 allosteric modulator. Exhibits species-specific activity; acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2) and a positive allosteric modulator of rat P2X7.

Product Specifications for GW 791343 hydrochloride

Molecular Weight

483.81

Formula

C20H24F2N4O.3HCl

Storage

Desiccate at RT

Purity

≥99% (HPLC)

Chemical Name

2-[(3,4-Difluorophenyl)amino]-N-[2-methyl-5-(1-piperazinylmethyl)phenyl]-acetamide trihydrochloride

CAS Number

309712-55-8

PubChem ID

9848159

InChI Key

WSBRAHWNJBXXJM-UHFFFAOYSA-N

SMILES

CC(C=C2)=C(NC(CNC3=CC=C(F)C(F)=C3)=O)C=C2CN1CCNCC1.Cl.Cl.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 48.38 100
DMSO 48.38 100

Preparing Stock Solutions for GW 791343 hydrochloride

The following data is based on the product molecular weight 483.81.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.07 mL 10.33 mL 20.67 mL
5 mM 0.41 mL 2.07 mL 4.13 mL
10 mM 0.21 mL 1.03 mL 2.07 mL
50 mM 0.04 mL 0.21 mL 0.41 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for GW 791343 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for GW 791343 hydrochloride

For research use only

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