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GW 791343 hydrochloride

3385 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
3385/10
3385/50
GW 791343 hydrochloride | CAS No. 309712-55-8 | P2X Receptor Modulators
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Description: Allosteric modulator of P2X7 receptors

Chemical Name: 2-[(3,4-Difluorophenyl)amino]-N-[2-methyl-5-(1-piperazinylmethyl)phenyl]-acetamide trihydrochloride

Purity: ≥99%

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Biological Activity

P2X7 allosteric modulator. Exhibits species-specific activity; acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2) and a positive allosteric modulator of rat P2X7.

Technical Data

M.Wt:
483.81
Formula:
C20H24F2N4O.3HCl
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at RT
CAS No:
309712-55-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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VersaClone cDNA Plasmids

Human P2RX7 (AAH11913) VersaClone cDNA

RDC0486

Rat P2X7/P2RX7 (NP_062129) VersaClone cDNA

RDC2259

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