Human Carbonic Anhydrase XIV/CA14 Alexa Fluor® 700-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: Carbonic Anhydrase XIV/CA14

Carbonic Anhydrase 14 (CA14) has a C-terminal transmembrane domain (aa 291 - 311) and a short cytoplasmic tail (aa 312 - 337). As a functioning enzyme of the CA family, it catalyzes the reversible hydration of CO2. CA14 is highly expressed in all parts of the central nervous system with lower expression in adult liver, heart, small intestine, colon, kidney, urinary bladder and skeletal muscle. The rhCA14 corresponds to the 272 aa ectodomain that has a predicted molecular mass of approximately 32 kDa and an apparent molecular mass of approximately 43 kDa in SDS-PAGE. The amino acid sequence of the human ectodomain shares 98%, 86%, 84%, and 83% identity with that of chimpanzee, bovine/dog, rat and mouse, respectively.

Product Datasheets