Human Common  beta  Chain APC‑conjugated Antibody

R&D Systems | Catalog # FAB906A

R&D Systems
Discontinued Product
FAB906A has been discontinued. View all Common beta Chain products.

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Mouse

Applications

Validated:

Flow Cytometry

Cited:

Flow Cytometry

Label

Allophycocyanin (Excitation = 620-650 nm, Emission = 660-670 nm)

Antibody Source

Polyclonal Goat IgG
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Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Common beta Chain
Gly23-Trp443
Accession # P32927

Specificity

Detects recombinant human (rh) Common beta  Chain in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) GM-CSF R alpha, rhG-CSF R and rhM-CSF R is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Human Common  beta  Chain APC‑conjugated Antibody

Detection of Common  beta  Chain antibody in Whole Blood Granulocytes antibody by Flow Cytometry.

Detection of Common beta Chain in Whole Blood Granulocytes by Flow Cytometry.

Whole blood granulocytes were stained with Goat Anti-Human Common beta Chain APC-conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB906A, filled histogram) or isotype control antibody (Catalog # IC108A, open histogram). View our protocol for Staining Membrane-associated Proteins.

Applications for Human Common  beta  Chain APC‑conjugated Antibody

Application
Recommended Usage

Flow Cytometry

10 µL/106 cells
Sample: Whole blood granulocytes

Spectra Viewer

Plan Your Experiments

Use our spectra viewer to interactively plan your experiments, assessing multiplexing options. View the excitation and emission spectra for our fluorescent dye range and other commonly used dyes.

Spectra Viewer

Flow Cytometry Panel Builder

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Save time and reduce costly mistakes by quickly finding compatible reagents using the Panel Builder Tool.

Advanced Features

  • Spectra Viewer - Custom analysis of spectra from multiple fluorochromes
  • Spillover Popups - Visualize the spectra of individual fluorochromes
  • Antigen Density Selector - Match fluorochrome brightness with antigen density
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Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

Supplied in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8° C. Do not use past expiration date. Protect from light.

Background: Common beta Chain

The common beta chain, also known as CD131, is a transmembrane protein that associates with the ligand-specific IL-3 R alpha, IL-5 R alpha, or GM-CSF R alpha proteins to form high affinity receptor complexes. beta c is expressed on a variety of hematopoietic cells.

Alternate Names

CD131, CSF2RB, GM-CSF R beta, IL-3 R beta, IL-5 R beta

Entrez Gene IDs

1439 (Human); 12983 (Mouse); 102143353 (Cynomolgus Monkey)

Gene Symbol

CSF2RB

UniProt

Additional Common beta Chain Products

Product Documents for Human Common  beta  Chain APC‑conjugated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human Common  beta  Chain APC‑conjugated Antibody

For research use only

Citations for Human Common  beta  Chain APC‑conjugated Antibody

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