Detects recombinant human (rh) Common beta Chain in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human (rh) GM-CSF R alpha, rhG-CSF R and rhM-CSF R is observed.
Polyclonal Goat IgG
Mouse myeloma cell line NS0-derived recombinant human Common beta Chain Gly23-Trp443 Accession # P32927
Supplied in a saline solution containing BSA and Sodium Azide.
Detection of Common beta Chain in Whole Blood Granulocytes by Flow Cytometry.
Whole blood granulocytes were stained with Goat Anti-Human Common beta Chain APC‑conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB906A, filled histogram) or isotype control antibody (Catalog # IC108A, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
12 months from date of receipt, 2 to 8 °C as supplied.
Background: Common beta Chain
The common beta chain, also known as CD131, is a transmembrane protein that associates with the ligand-specific IL-3 R alpha, IL-5 R alpha, or GM-CSF R alpha proteins to form high affinity receptor complexes. beta c is expressed on a variety of hematopoietic cells.
Entrez Gene IDs:
1439 (Human); 12983 (Mouse)
beta, low-affinity; CD131 antigen; CD131; CDw131; colony stimulating factor 2 receptor, beta, low-affinity(granulocyte-macrophage); Common beta Chain; CSF2RB; cytokine receptor common subunit beta; GM-CSF R beta; GM-CSF/IL-3/IL-5 receptor common beta subunit; GM-CSF/IL-3/IL-5 receptor common beta-chain; IL-3 R beta; IL3RB; IL-5 R beta; interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3receptor, beta (high affinity)
R&D Systems personnel manually curate a database that contains references using R&D Systems products.
The data collected includes not only links to publications in PubMed,
but also provides information about sample types, species, and experimental conditions.
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