MMP-3 (Matrix Metalloproteinase 3; Stromelysin-1) is a zinc and calcium dependent endopeptidase that can degrade Collagen alpha-chains, Aggrecan, Laminin, Fibronectin, Elastin, Casein, alpha-1 Antitrypsin, Myelin Basic Protein, IL-1 beta, IGFBP-3, pro-MMP-1, pro-MMP-7, pro-MMP-8, pro-MMP-9, and pro-MMP-13. MMP-3 does not cleave the triple helical region of interstitial collagens, a characteristic which distinguishes the stromelysins from the collagenases. MMP-3 is expressed by fibroblasts, chrondrocytes, osteoblasts, endothelial cells, smooth muscle cells, and macrophages.
Human MMP-3 (AAA36321.1) VersaClone cDNA
R&D Systems | Catalog # RDC3092
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Formulation, Preparation, and Storage
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Background: MMP-3
Long Name
Matrix Metalloproteinase 3
Alternate Names
MMP3, Stromelysin 1
Gene Symbol
MMP3
UniProt
Additional MMP-3 Products
Product Documents for Human MMP-3 (AAA36321.1) VersaClone cDNA
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Human MMP-3 (AAA36321.1) VersaClone cDNA
For research use only
Related Research Areas
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