Human/Mouse MSK2 Alexa Fluor® 594-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB2310T-100UG

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Human/Mouse MSK2 Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity
Human, Mouse
Specificity
Detects human and mouse MSK2 in Western blots. Does not detect recombinant human MSK1.
Source
Monoclonal Rat IgG2a Clone # 261034
Purification
Protein A or G purified
Immunogen
E. coli-derived recombinant human MSK2
Met1-Ser772
Accession # O75676
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: MSK2

Mitogen- and stress-activated protein kinase 2 (MSK2), also known as ribosomal protein S6 kinase B (RSKB) and RPS6KA4, belongs to the family of AGC kinases. Both MSK2 and the related MSK1 have two kinase domains connected by a regulatory linker region and are activated by the mitogen-activated protein kinases ERK1, ERK2, and p38. Nuclear MSK phosphorylates and activates a number of transcription factors, including ATF1 and CREB.

Long Name
Mitogen- and Stress-activated Protein Kinase 2
Entrez Gene IDs
8986 (Human); 56613 (Mouse)
Alternate Names
MSK2; ribosomal protein S6 kinase, 90kDa, polypeptide 4; RPS6KA4; RSKB

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