Human TSG101 Alexa Fluor® 350-conjugated Antibody

Catalog #: FAB11438U Datasheet / COA / SDS

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FAB11438U-100UG

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All TSG101 Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human TSG101 Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects TSG101 in direct ELISA.

Source

Monoclonal Mouse IgG2a Clone # 1065908

Purification

Protein A or G purified

Immunogen

TSG101 containing synthetic peptide
Accession # Q99816

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration

Sample

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: TSG101

TSG101 is an essential member of the ESCRT-1 complex which regulates the sorting of ubiquitinated proteins to endosomes, facilitating vesicular trafficking and is implicated in normal development. It is also involved in regulating transcription, protein sorting, biogenesis of multi-vesicular bodies, and viral budding. Dysregulation of ESCRT proteins occurs in the development of various human diseases, including many types of cancers and neurodegenerative diseases. TSG101 is an established cancer-associated gene and truncated aberrantly spliced mRNAs have been reported in various types of cancer. TSG101 is also commonly used as a marker protein for exosomes.

Long Name

Tumor Susceptibility 101

Entrez Gene IDs

7251 (Human)

Alternate Names

ESCRT-I complex subunit TSG101; TSG10; TSG101; tumor susceptibility gene 10; tumor susceptibility gene 101 protein; tumor susceptibility gene 101; tumor susceptibility protein; VPS23