Human UNC5H4 (NP_543148) VersaClone cDNA

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R&D Systems VersaClone cDNA Plasmids
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Human UNC5H4 (NP_543148) VersaClone cDNA Summary


Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

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Background: UNC5H4

Members of the UNC5H family are best known as receptors for the axon guidance molecule netrin. Structurally, UNC5Hs have two Ig and two thrombospondin type 1 domains in their extracellular region, and a conserved ZU-5 domain, a deleted in colorectal cancer (DCC)-binding domain, and a C-terminal death domain in their cytoplasmic region. In general, they mediate the chemorepulsive effects of netrin, while the other netrin receptor subtype, DCC, mediates attraction. Members of the UNC5H family have also been implicated as tumor suppressors and regulators of apoptosis.

Long Name
Netrin Receptor UNC5D
Entrez Gene IDs
137970 (Human)
Alternate Names
FLJ16019; KIAA1777Unc5h4; netrin receptor UNC5D; netrin receptor Unc5h4; PRO34692; Protein unc-5 homolog 4; Protein unc-5 homolog D; unc-5 homolog 4; unc-5 homolog D (C. elegans); UNC5D; UNC5H4


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