Potent and highly selective histamine H3
receptor agonist (pEC50
= 9.74) that displays 300-fold selectivity over the H4
values are 9.07 and 6.61 respectively). Does not bind to H1
receptors at concentrations up to 10 μ
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All Tocris products are intended for laboratory research use only.
Identification of 4-(1H-imidazol-4(5)-ylmethyl)pyridine (immethridine) as a novel, potent, and highly selective histamine H3 receptor agonist.
Kitbunnadaj et al.