ING-2 AM
Tocris Bioscience | Catalog # 7870
Key Product Details
Description
Wavelength
Product Description
ING-2 AM is a membrane-permeable fluorescent sodium ion (Na+) indicator. It binds to sodium (Kd = 20 mM). Excitation and emission maxima (λ) are 525 and 545 nm, respectively. It displays 20-fold selectivity over K+ ions. It is used in in vitro and in situ to detect real-time sodium influx.It is recommended to prepare stock solutions in DMSO.
Optical Data
| λabs | 525 nm |
| λem | 545 nm |
| Cell Permeable | Yes |
| Application | Confocal microscopy, Flow cytometry, Two-photon microscopy |
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Product Specifications for ING-2 AM
Molecular Weight
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Chemical Name
CAS Number
PubChem ID
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The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Calculators
Background References
References are publications that support the biological activity of the product.
- Roder ANG-2 for quantitative Na(+) determination in living cells by time-resolved fluorescence microscopy. Photochem.Photobiol.Sci. 2014 PMID: 25311309
- Blömer Ultrafast sodium imaging of the axon initial segment of neurons in mouse brain slices. Curr.Protoc. 2021 PMID: 33657273
- Naumann Photophysical properties of Na+ -indicator dyes suitable for quantitative two-photon fluorescence-lifetime measurements. J.Microsc. 2018 PMID: 30191999
- Gregoriades Genetic and pharmacological inactivation of apical Na+-K+-2Cl- cotransporter 1 in choroid plexus epithelial cells reveals the physiological function of the cotransporter. Am.J.Physiol.Cell Physiol. 2019 PMID: 30576237
Product Documents for ING-2 AM
Certificate of Analysis
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Product Specific Notices for ING-2 AM
For research use only
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