Chemical Name: 6-(2,5-Dichlorophenyl)-1,3,5-triazine-2,4-diamine maleate
Biological ActivityPhosphodiesterase 4 (PDE4) inhibitor that displays gastroprotective properties. Prevents gastric mucosal injury induced by monochloramine and ischemia-reperfusion. Activates gap-junctional intercellular communication improving gastric mucosal barrier function. Inhibits superoxide production in human neutrophils and inhibits in vitro and in vivo angiogenesis.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Inhibition of breast cancer regrowth and pulmonary metastasis in nude mice by anti-gastric ulcer agent, irsogladine.
Nozaki et al.
Breast Cancer Res.Treat., 2004;83:195
Phosphodiesterase type IV inhibitors prevent ischemia-reperfusion-induced gastric injury in rats.
Kyoi et al.
Irsogladine, an anti-ulcer drug, suppresses superoxide production by inhibiting phosphodiesterase type 4 in human neutrophils.
Kyoi et al.
Life Sci., 2004;76:71
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for Irsogladine maleate
There are currently no reviews for this product. Be the first to review Irsogladine maleate and earn rewards!
Have you used Irsogladine maleate?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image