Catalog Number: 1565
Alternate Names: TI-JIP
Biological Activity
Peptide inhibitor of c-Jun N-terminal kinase (JNK), based on residues 153-163 of JNK-interacting protein-1 (JIP-1). Binds to JNK with affinity in the micromolar range and minimally inhibits p38 and ERK.
Technical Data
  • M.Wt:
    1341.6
  • Formula:
    C61H104N20O14
  • Sequence:
    RPKRPTTLNLF

    (Modifications: Phe-11 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    438567-88-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Identification of the critical features of a small peptide inhibitor of JNK activity.
    Barr et al.
    J.Biol.Chem., 2002;277:10987
Citations:

The citations listed below are publications that use Tocris products. Selected citations for JIP-1 (153-163) include:

1 Citations: Showing 1 - 1

  1. The Ser/Thr kinase MAP4K4 drives c-Met-induced motility and invasiveness in a cell-based model of SHH medulloblastoma.
    Authors: Kumar Et al.
    Springerplus 2015;4:19

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