Peptide inhibitor of c-Jun N-terminal kinase (JNK), based on residues 153-163 of JNK-interacting protein-1 (JIP-1). Binds to JNK with affinity in the micromolar range and minimally inhibits p38 and ERK.
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Identification of the critical features of a small peptide inhibitor of JNK activity.
Barr et al.
The citations listed below are publications that use Tocris products. Selected citations for JIP-1 (153-163) include:
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