Catalog Number: 1342
Chemical Name: (1-Pentyl-1H-indol-3-yl)-1-naphthalenylmethanone
Biological Activity
Potent cannabinoid receptor agonist with mild selectivity for CB2 (Ki values are 2.94 and 9.0 nM for CB2 and CB1 receptors respectively).
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding.
    Aung et al.
    Drug Alcohol Depend., 2000;60:133
  2. The third transmembrane helix of the cannabinoid receptor plays a role in the selectivity of aminoalkylindoles for CB2, peripheral cannabinoid receptor.
    Chin et al.
    J.Pharmacol.Exp.Ther., 1999;291:837
  3. 3-Indolyl-1-naphthylmethanes: New cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB1 cannabinoid receptor.
    Huffman et al.
    Bioorg.Med.Chem., 2003;11:539
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