JWH 018

Key Product Details

Product Description

Potent cannabinoid receptor agonist with mild selectivity for CB₂ (K_i values are 2.94 and 9.0 nM for CB₂ and CB₁ receptors respectively).

Product Specifications for JWH 018

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for JWH 018

The following data is based on the product molecular weight 341.45.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.93 mL	14.64 mL	29.29 mL
5 mM	0.59 mL	2.93 mL	5.86 mL
10 mM	0.29 mL	1.46 mL	2.93 mL
50 mM	0.06 mL	0.29 mL	0.59 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 9 publications citing the usage of this product.

• Chin The third transmembrane helix of the cannabinoid receptor plays a role in the selectivity of aminoalkylindoles for CB2, peripheral cannabinoid receptor. J.Pharmacol.Exp.Ther. 1999 PMID: 10525107
• Huffman 3-Indolyl-1-naphthylmethanes: New cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB₁ cannabinoid receptor. Bioorg.Med.Chem. 2003 PMID: 12538019
• Aung Influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB₁ and CB₂ receptor binding. Drug Alcohol Depend. 2000 PMID: 10940540

Product Documents for JWH 018