Luzindole
Tocris Bioscience | Catalog # 0877
Key Product Details
Description
Product Description
Luzindole is a melatonin antagonist.
Product Specifications for Luzindole
Molecular Weight
Formula
Storage
Purity
Chemical Name
CAS Number
PubChem ID
InChI Key
SMILES
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 29.24 | 100 | |
| Ethanol | 29.24 | 100 |
Preparing Stock Solutions for Luzindole
The following data is based on the product molecular weight 292.38.
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.42 mL | 17.10 mL | 34.20 mL |
| 5 mM | 0.68 mL | 3.42 mL | 6.84 mL |
| 10 mM | 0.34 mL | 1.71 mL | 3.42 mL |
| 50 mM | 0.07 mL | 0.34 mL | 0.68 mL |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 66 publications citing the usage of this product.
- Dubocovich Anti-depressant-like activity of the melatonin receptor antagonist, luzindole (N-0774), in mouse behavioural despair test. Eur.J.Pharmacol. 1990 PMID: 2168835
- Dubocovich Melatonin receptors: are there multiple subtypes? TiPS 1995 PMID: 7762083
- Dubocovich Luzindole (N-0774): a novel melatonin receptor antagonist. J.Pharmacol.Exp.Ther. 1988 PMID: 2843633
Product Documents for Luzindole
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Luzindole
For research use only
Citations for Luzindole
Customer Reviews for Luzindole (1)
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Species: HumanAssay Type: In VitroCell Line/Tissue: HepG2, and Huh,Verified Customer | Posted 11/30/2022It is a good MT1/MT2 agonist. Can activate cAMP and its downstream targets. Used at 10 uM concentration
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