Chemical Name:(S)-(+)-α-Amino-4-carboxy-2-methylbenzeneacetic acid
Biological Activity A selective mGlu1a receptor antagonist, with an IC50 value of 8.8 μM for blockade of quisqualate-induced phosphoinositide hydrolysis vs. > 100 μM for mGlu5a, and negligible action on group II and III receptors. Also available as part of the Group I mGlu Receptor Tocriset™.
Soluble to 100 mM in 1.1eq. NaOH
Desiccate at RT
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
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