Catalog Number: 2698
Alternate Names: Galanin-(2-13)-Glu-His-(Pro)3-(Ala-Leu)2-Ala-amide
Biological Activity
Selective galanin GAL2 receptor antagonist (Ki values are 13.1 and 420 nM for GAL2 and GAL1 receptors respectively). Blocks the pro-nociceptive effect of GAL2 receptor agonists.
Technical Data
  • M.Wt:
  • Formula:
  • Sequence:

    (Modifications: Ala-22 = C-terminal amide)

  • Solubility:
    Soluble to 1 mg/ml in 30% acetonitrile
  • Storage:
    Desiccate at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Activation of peripheral galanin receptors: differential effects on nociception.
    Jimenez-Andrade et al.
    Pharmacol.Biochem.Behav., 2006;85:273
  2. M871 - a novel peptide antagonist selectively recognizing the galanin receptor type 2.
    Sollenburg et al.
    Int.J.Pept.Res.Ther., 2006;12:115

The citations listed below are publications that use Tocris products. Selected citations for M871 include:

4 Citations: Showing 1 - 4
Filter your results:

  1. Involvement of galanin and galanin receptor 2 in nociceptive modulation in anterior cingulatecortex of normal rats and rats with mononeuropathy
    Authors: Zhang
    Sci Rep 2017;7:45930
  2. Galanin modulates the neural niche to favour perineural invasion in head and neck cancer.
    Authors: Scanlon Et al.
    Int J Neuropsychopharmacol 2015;6:6885
  3. A role for galanin N-terminal fragment (1-15) in anxiety- and depression-related behaviors in rats.
    Authors: Millón Et al.
    Immun Inflamm Dis 2015;18
  4. A role for galanin N-terminal fragment (1-15) in anxiety- and depression-related behaviors in rats.
    Authors: Millòn Et al.
    Int.J.Neuropsychopharmacol. 2014;18

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