Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

DyLight 680 (Excitation = 692 nm, Emission = 712 nm)

Antibody Source

Polyclonal Sheep IgG
View all MDGA1 Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human MDGA1
Gln19-Gly931
Accession # Q8NFP4

Specificity

Detects human MDGA1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 10% cross-reactivity with recombinant human MDGA2 is observed.

Clonality

Polyclonal

Host

Sheep

Isotype

IgG

Applications for MDGA1 Antibody [DyLight 680]

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: MDGA1

MDGA-1 (MAM domain-containing GPI anchor protein 1) is a 135-140 kDa, novel member of the Ig-superfamily. It is expressed on embryonic neurons destined for cortical layers 2/3, as well as migrating basilar pontine neurons and D1 interneurons of the spinal cord. Human proMDGA-1 is 937 amino acids (aa) in length (SwissProt #:Q8NFP4). It is a GPI-linked glycoprotein that contains six consecutive Ig-like domains (aa #24-631), followed by one fibronectin type III domain (aa #640-739), a MAM region (aa #751-918), and a cleavable propeptide (aa #933-955). There are at least three potential variants. One shows a 48 aa substitution for aa #936-955, a second shows a 58 aa substitution for aa #847-955, and a third shows a 51 aa substitution for aa #537-955. Over aa #19-931, human MDGA-1 is 95% aa identical to mouse MDGA-1.

Long Name

MAM Domain Containing Glycosylphosphatidylinositol Anchor 1

Alternate Names

GPIM, MAMDC3

Gene Symbol

MDGA1

Additional MDGA1 Products

Product Documents for MDGA1 Antibody [DyLight 680]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for MDGA1 Antibody [DyLight 680]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Related Research Areas

Immunoglobulin Superfamily CAMs

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FAQs

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