Melanocyte-stimulating hormone release inhibiting factor
Biological ActivityMelanocyte-stimulating hormone release inhibiting factor is a inhibitor of melanocyte-stimulating hormone (MSH) release. Blocks the release of α-MSH, increases brain dopamine levels and antagonizes physiological and behavioral opioid effects in vivo.
(Modifications: Gly-3 = C-terminal amide)
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Inhibitory influences of FMRFamide and PLG on stress-induced opioid analgesia and activity.
Kavaliers and Hirst
Brain Res., 1986;372:370
Synthetic melanocyte stimulating hormone release inhibiting factor (MIF). Part III: effect of L-prolyl-N-MthD.-leucyl-glycinamide and MIF on biogenic amine turnover.
Pugsley and Lippmann
Pharmacology of L-Prolyl-L-Leucyl-Glycinamide (PLG): a review.
Mishra et al.
Methods Find.Exp.Clin.Pharmacol., 1983;5:203
Pharmacological studies with a tripeptide, Prolyl-Leucyl Glycine amide.
Plotnikoff and Kastin
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