Chemical Name: [(8β)-1,6-Dimethylergolin-8-yl)methyl]carbamic acid phenylmethyl ester
Biological ActivityMetergoline is an antagonist at 5-HT1/5-HT2 with activity at 5-HT1D. Has moderate affinity for 5-HT6 and high affinity for 5-HT7.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Complete Your Research
Complete Your Experiment
Pharmacological characterization of serotonin receptor subtypes involved in vasopressin and plasma renin activity responses to serotonin agonists.
Bagdy et al.
Effects of various serotonin receptor subtype selective antagonists alone and on m-chlorophenylpiperazine-induced neuroendocrine changes in rats.
Aulakh et al.
Agonist activity of sumatr. and metergoline at the human 5-HT1Dβ receptor in the action of sumatr.
Miller et al.
Respiratory and cardiovascular effects of the mu-opioid receptor agonist [Lys7]dermorphin in awake rats.
Negri et al.
Citations for Metergoline
The citations listed below are publications that use Tocris products. Selected citations for Metergoline include:
4 Citations: Showing 1 - 4
Dezocine exhibits antihypersensitivity activities in neuropathy through spinal μ-opioid receptoractivation and NE reuptake inhibition.
Sci Rep 2017;7:43137
A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors.
Authors: Chan Et al.
PLoS Pathog 2016;12:e1005651
Metergoline inhibits the neuronal Nav1.2 voltage-dependent Na(+) channels expressed in Xenopus oocytes.
Authors: Lee Et al.
Acta Pharmacol Sin 2014;35:862
Neuregulin-1 enhances depolarization-induced GABA release.
Authors: Woo Et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for Metergoline
There are currently no reviews for this product. Be the first to review Metergoline and earn rewards!
Have you used Metergoline?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image