Metergoline

  ( 4 citations )    
Product Datasheet
Catalog Number:0590
Chemical Name:[(8β)-1,6-Dimethylergolin-8-yl)methyl]carbamic acid phenylmethyl ester
Product Details
Citations (4)
Supplemental Products
Reviews
Biological Activity
Antagonist at 5-HT 15-HT 2 with activity at 5-HT 1D. Has moderate affinity for 5-HT 6 and high affinity for 5-HT 7.
Technical Data
  • M.Wt:
    403.52
  • Formula:
    C25H29N3O2
  • Solubility:
    Soluble to 100 mM in DMSO
  • Storage:
    Store at RT
  • CAS No:
    17692-51-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Metergoline include:

4 Citations: Showing 1 - 4
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  1. Dezocine exhibits antihypersensitivity activities in neuropathy through spinal μ-opioid receptoractivation and norepinephrine reuptake inhibition.
    Authors: Wang
    Sci Rep  2017;7:43137
  2. A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors.
    Authors: Chan Et al.
    PLoS Pathog  2016;12:e1005651
  3. Metergoline inhibits the neuronal Nav1.2 voltage-dependent Na(+) channels expressed in Xenopus oocytes.
    Authors: Lee Et al.
    Acta Pharmacol Sin  2014;35:862
  4. Neuregulin-1 enhances depolarization-induced GABA release.
    Authors: Woo Et al.
    Neuron  2007;54:599

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VersaClone cDNA Plasmids
Description Application Cat# Citations Images  

Human 5-HT7 (NP_000863) VersaClone cDNA

RDC0251
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Human 5-HT7 (NP_062874) VersaClone cDNA

RDC0252
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Human 5-HT1D (NP_000855) VersaClone cDNA

RDC0285
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