mGluR3 Antibody (SR1543) - BSA Free

Novus Biologicals | Catalog # NBP3-22382

Recombinant Monoclonal Antibody
Novus Biologicals
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1543 expressed in HEK293

Format

BSA Free
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Product Specifications

Immunogen

A synthesized peptide derived from human mGluR3 (Uniprot #: Q14832)

Specificity

Detects endogenous levels of total mGluR3

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

330 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for mGluR3 Antibody (SR1543) - BSA Free

Western Blot: mGluR3 Antibody (SR1543) [NBP3-22382] -

Western Blot: mGluR3 Antibody (SR1543) [NBP3-22382] - Western blot analysis using NBP3-22382 in Human cerebellum lysate.

Applications for mGluR3 Antibody (SR1543) - BSA Free

Application
Recommended Usage

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: mGluR3

The Metabotropic Glutamate Receptor GRM3 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. Metabotropic glutamate receptor Group II includes the GRM2 and GRM3 receptors that are linked to inhibition of the cyclic AMP signaling cascade. GRM3 has been reported in various regions of the brain and spinal cord. ESTs have been isolated from brain, embryo, fetal lung/testis/B-cell, nerve, placenta, prostate, and vessel libraries. Caution: GLUR3 refers to Ionotropic Glutamate Receptor 3, not to Metabotropic Glutamate Receptor 3 (mGLUR3).

Long Name

Metabotropic Glutamate Receptor 3

Alternate Names

GPRC1C, GRM3

Gene Symbol

GRM3

Additional mGluR3 Products

Product Documents for mGluR3 Antibody (SR1543) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for mGluR3 Antibody (SR1543) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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