Midazolam hydrochloride

Tocris Bioscience | Catalog # 2832

Benzodiazepine agonist
Tocris Bioscience
Discontinued Product
2832 has been discontinued. View all GABA-A Receptor Benzodiazepines products.

Key Product Details

Description

Benzodiazepine agonist

Alternative Names

Dormicum,Ro 21-3981/001
View all GABA-A Receptor Benzodiazepines »

Product Description

Midazolam hydrochloride is a sedative/hypnotic agent that acts at the GABAA receptor benzodiazepine modulatory site.

Product Specifications for Midazolam hydrochloride

Molecular Weight

362.23

Formula

C18H13ClFN3.HCl

Storage

Desiccate at RT

Purity

≥99% (HPLC)

Chemical Name

8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine hydrochloride

CAS Number

59467-96-8

PubChem ID

43032

InChI Key

PLYSCVSCYOQVRP-UHFFFAOYSA-N

SMILES

FC(C=CC=C4)=C4C3=NCC1=CN=C(C)N1C2=CC=C(Cl)C=C23.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 9.06 25

Preparing Stock Solutions for Midazolam hydrochloride

The following data is based on the product molecular weight 362.23.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.25 mM 11.04 mL 55.21 mL 110.43 mL
1.25 mM 2.21 mL 11.04 mL 22.09 mL
2.5 mM 1.10 mL 5.52 mL 11.04 mL
12.5 mM 0.22 mL 1.10 mL 2.21 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Midazolam hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Midazolam hydrochloride

For research use only

Related Research Areas

GABA Receptors

Citations for Midazolam hydrochloride

Customer Reviews for Midazolam hydrochloride (2)

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2 Customer Ratings
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  • Midazolam potentiates response of GABA-A receptors even in low concentration
    Name: Anonymous
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: Cerebellum
    Verified Customer | Posted 08/17/2019
    Midazolam was used to test a response of GABA-A receptors in cerebellar granule cells; the compound has shown a clear potentiatory effect. Figure: evoked EPSCs under control (black) and with 10 microM of Midazolam in perfusion solution (white).
    Midazolam hydrochloride 2832
  • for a study
    Name: Anonymous
    Verified Customer | Posted 12/01/2017
    It worked as planned, never had any issues.

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