Mineralocorticoid R/NR3C2 Antibody (NR3C2/4900)

Novus Biologicals | Catalog # NBP3-26820

Recombinant Monoclonal Antibody
Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Mouse IgG1 kappa Clone # NR3C2/4900
View all Mineralocorticoid R/NR3C2 Primary Antibodies »

Product Specifications

Immunogen

Recombinant fragment (around aa601-673) of human Mineralocorticoid R/NR3C2 protein

Localization

Nucleus

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C. Non-hazardous. No MSDS required.

Scientific Data Images for Mineralocorticoid R/NR3C2 Antibody (NR3C2/4900)

Mineralocorticoid R/NR3C2 Antibody (NR3C2/4900)

Immunohistochemistry-Paraffin: Mineralocorticoid R/NR3C2 Antibody (NR3C2/4900) [NBP3-26820 ] -

Formalin-fixed, paraffin-embedded human kidney stained with NR3C2 Mouse Monoclonal Antibody (NR3C2/4900). Inset: PBS instead of primary antibody; secondary only negative control.

Applications for Mineralocorticoid R/NR3C2 Antibody (NR3C2/4900)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1-2ug/ml for 30 minutes at RT
Application Notes
Immunohistochemistry-Paraffin 1-2ug/ml for 30 minutes at RT. Optimal dilution for a specific application should be determined.. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: Mineralocorticoid R/NR3C2

Steroid receptors are ligand dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Mineralocorticoids are a family of steroids, secreted by the adrenal cortex, necessary for the regulation of a number of metabolic processes including electrolyte regulation. These compounds exert their effect through their interaction with the mineralocorticoid receptor and that complex's subsequent association with DNA. Given the function of mineralocorticoids, it is not surprising to find that the kidney is a primary target organ for mineralocorticoids and that this organ has been shown to contain Mineralocorticoid Receptor.

Long Name

Mineralocorticoid Receptor

Alternate Names

MineralocorticoidR, MLR, NR3C2

Gene Symbol

NR3C2

Additional Mineralocorticoid R/NR3C2 Products

Product Documents for Mineralocorticoid R/NR3C2 Antibody (NR3C2/4900)

Certificate of Analysis

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Product Specific Notices for Mineralocorticoid R/NR3C2 Antibody (NR3C2/4900)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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