Non-peptide apelin receptor agonist (EC50
= 3.7 μ
M); exhibits >21-fold selectivity over the closely related angiotensin 1 receptor (EC50
= >79 μ
Soluble to 50 mM in DMSO
Store at -20°C
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Apelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular system.
Yang et al.
Trends Pharmacol Sci., 2015;36:560
Functional agonists of the apelin (APJ) receptor.
Khan et al.
Probe Reports from the NIH Molecular Libraries Program, 2011;