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ML 402

6888 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6888/50
6888/10
Two-P Potassium Channels Activators Small Molecule
1 Image
Description: Selective TREK channel activator

Chemical Name: N-[2-(4-Chloro-2-methylphenoxy)ethyl]-2-thiophenecarboxamide

Purity: ≥98%

Product Details
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Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Selective TREK channel activator. Selectively activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2) with no significant effect at K2P4.1 channels (TRAAK).

Technical Data

M.Wt:
295.78
Formula:
C14H14ClNO2S
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
298684-44-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. K2P2.1 (TREK-1)-activator complexes reveal a cryptic selectivity filter binding site.
    Lolicato et al.
    Nature, 2017;547:364

Product Datasheets

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Reconstitution Calculator

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