Motilin (human, porcine)
Tocris Bioscience | Catalog # 2264
Endogenous peptide regulator of gastrointestinal motility
Discontinued Product
2264 has been discontinued.
View all Motilin Receptor Peptides products.
Key Product Details
Description
Endogenous peptide regulator of gastrointestinal motility
Product Description
Motilin (human, porcine) is an endogenous motilin receptor ligand (Ki = 2.3 nM) that regulates gastrointestinal motor function. Stimulates contraction of gut smooth muscle (EC50 = 1 nM) and increases pepsin release.
Product Specifications for Motilin (human, porcine)
Molecular Weight
2699.07
Formula
C120H188N34O35S
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
52906-92-0
PubChem ID
16136567
InChI Key
LVRVABPNVHYXRT-BQWXUCBYSA-N
SMILES
[H]N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(O)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Solubility
| Solubility | Soluble to 1mg/ml in water |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.
- Coulie Identification of peptide ligand-binding domains within the human motilin receptor using photoaffinity labeling. J.Biol.Chem. 2001 PMID: 11461914
- Huang Signaling pathways mediating gastrointestinal smooth muscle contraction and MLC20 phosphorylation by motilin receptors. Am.J.Physiol.Gastrointest.Liver Physiol. 2005 PMID: 15591586
- Itoh Motilin and clinical application. Peptides 1997 PMID: 9210180
Product Documents for Motilin (human, porcine)
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Motilin (human, porcine)
For research use only
Citations for Motilin (human, porcine)
Customer Reviews for Motilin (human, porcine) (1)
5 out of 5
1 Customer Rating
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Species: HumanAssay Type: In VitroVerified Customer | Posted 01/05/2018Soluble in H2OCaused contraction of GI smooth muscle 10-300 nM
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