Home / CCDC134 / Mouse CCDC134 Alexa Fluor® 350-conjugated Antibody

Mouse CCDC134 Alexa Fluor® 350-conjugated Antibody

Catalog #: FAB7786U Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB7786U-100UG
Product Details
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse CCDC134 Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse CCDC134 in direct ELISAs. In direct ELISAs, 100% cross-reactivity with recombinant human CCDC134 is observed.
Source
Monoclonal Rat IgG2a Clone # 815606
Purification
Protein A or G purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse CCDC134
Ala23-Leu229
Accession # Q8C7V8
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: CCDC134

Coiled-coil domain containing 134 (CCDC134) is a widely expressed glycoprotein that is secreted as a 38 kDa molecule. CCDC134 overexpression inhibits kinase activity in the Raf-1/MEK/ERK and JNK/SAPK pathways. In humans, CCDC134 polymorphisms are associated with reduced levels of Amyloid beta peptide (1-42) in the cerebrospinal fluid, a potential biomarker for Alzheimer’s disease. Alternative splicing of mouse CCDC134 generates a short isoform that lacks the N-terminal 37 amino acids including the signal peptide. Mouse CCDC134 shares 90% and 95% aa sequence identity with human and rat CCDC134, respectively.

Long Name
Coiled-coil Domain Containing 134
Entrez Gene IDs
79879 (Human); 76457 (Mouse); 500909 (Rat)
Alternate Names
CCDC134; coiled-coil domain containing 134; coiled-coil domain-containing protein 134; dJ821D11.3; FLJ22349; MGC21013

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