Mouse UGRP1/SCGB3A2 Alexa Fluor® 750-conjugated Antibody

Catalog #: AF3465S Datasheet / COA / SDS

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AF3465S-100UG

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Mouse UGRP1/SCGB3A2 Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse UGRP1/SCGB3A2 isoforms C and A in direct ELISAs and Western blots. It is also expected to recognize isoform B in direct ELISAs and Western blots. In Western blots, approximately 15% cross-reactivity with recombinant human UGRP1 is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant mouse UGRP1/SCGB3A2 isoform C
Leu22-Leu139
Accession # Q920H1

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: UGRP1/SCGB3A2

UGRP-1, also known as secretoglobin family 3A member 2 (SCGB3A2) and HIN-2, is a secreted homodimeric protein that is highly expressed in epithelial cells of the airway. By alternative splicing events, three isoforms (A, B, C) that differ in their C-terminal regions, exist. UGRP-1 has been shown to bind MARCO (macrophage scavenger receptor with collagenous structure), which is expressed by alveolar macrophages. UGRP1 has been suggested to play a role in lung inflammation. Mature mouse UGRP1 isoform A shares 86% and 81% amino acid sequence identity with rat and human mature UGRP1, respectively.

Long Name

Uteroglobin-related Protein 1

Entrez Gene IDs

117156 (Human); 117158 (Mouse)

Alternate Names

LU103; Pneumo secretory protein 1; PnSP-1; PNSP1secretoglobin family 3A member 2; SCGB3A2; secretoglobin, family 3A, member 2; UGRP1; UGRP1pnSP-1; Uteroglobin-related protein 1