Mouse UGRP1/SCGB3A2 Biotinylated Antibody

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BAF3465
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Mouse UGRP1/SCGB3A2 Biotinylated Antibody Summary

Species Reactivity
Mouse
Specificity
Detects mouse UGRP1/SCGB3A2 isoforms C and A in Western blots. It is also expected to recognize isoform B in Western blots. In Western blots, approximately 5% cross-reactivity with recombinant human UGRP1 is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant mouse UGRP1/SCGB3A2 isoform C
Leu22-Leu139
Accession # Q920H1
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Label
Biotin

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Mouse UGRP1/SCGB3A2

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: UGRP1/SCGB3A2

UGRP-1, also known as secretoglobin family 3A member 2 (SCGB3A2) and HIN-2, is a secreted homodimeric protein that is highly expressed in epithelial cells of the airway. By alternative splicing events, three isoforms (A, B, C) that differ in their C-terminal regions, exist. UGRP-1 has been shown to bind MARCO (macrophage scavenger receptor with collagenous structure), which is expressed by alveolar macrophages. UGRP1 has been suggested to play a role in lung inflammation. Mature mouse UGRP1 isoform A shares 86% and 81% amino acid sequence identity with rat and human mature UGRP1, respectively.

Long Name
Uteroglobin-related Protein 1
Entrez Gene IDs
117156 (Human); 117158 (Mouse)
Alternate Names
LU103; Pneumo secretory protein 1; PnSP-1; PNSP1secretoglobin family 3A member 2; SCGB3A2; secretoglobin, family 3A, member 2; UGRP1; UGRP1pnSP-1; Uteroglobin-related protein 1

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