MRS 1334

Key Product Details

Product Description

MRS 1334 is a potent and highly selective antagonist for the human adenosine A₃ receptor. K_i values are 2.69 nM at hA₃, and > 100 μM at rat A₁ and rat A_2A receptors.

Licensing Information

Sold with the permission of the NIH, US Patent 60/029,855

Product Specifications for MRS 1334

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for MRS 1334

The following data is based on the product molecular weight 522.56.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.91 mL	9.57 mL	19.14 mL
5 mM	0.38 mL	1.91 mL	3.83 mL
10 mM	0.19 mL	0.96 mL	1.91 mL
50 mM	0.04 mL	0.19 mL	0.38 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 15 publications citing the usage of this product.

• Li Structure-activity relationships and molecular modeling of 3,5-diacyl-2,4-dialkylpyridine derivatives as selective A₃ adenosine receptor antagonists. J.Med.Chem. 1998 PMID: 9703464
• Corriden Adenosine-A₃ receptors in neutrophil microdomains promote the formation of bacteria-tethering cytonemes. EMBO.Rep. 2013 PMID: 23817552
• Baraldi and Borea New potent and selective human adenosine A₃ receptor antagonists. TiPS 2000 PMID: 11121831

Product Documents for MRS 1334