Catalog Number: 0432
Chemical Name: 1-(3-Chlorophenylamino)-4-phenylphthalazine
Biological Activity
Specific inhibitor of cyclic GMP phosphodiesterase, selective for PDE5 (IC50 = 0.5 μM).
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 50 mM in DMSO and to 5 mM in ethanol
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Effect of 1-(3-chloroanilino)-4-phenylphthalazine (MY-5445), a specific inhibitor of cyclic GMP phosphodiesterase, on human platelet aggregation.
    Hagiwara et al.
    J.Pharmacol.Exp.Ther., 1984;228:467
  2. Selective inhibitors of three forms of cyclic nucleotide phosphodiesterase, basic and potential clinical applications.
    Hidaka and Endo et al.
    Adv.Cyclic Nucleotide Protein Phosphorylation Res., 1984;16:245
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