N-(3-Oxododecanoyl)-L-homoserine lactone

Catalog # Availability Size / Price Qty
6548/10
6548/50
N-(3-Oxododecanoyl)-L-homoserine lactone | CAS No. 168982-69-2 | Immunosuppressants
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Description: Bacterial quorum sensing autoinducer; immunomodulator

Chemical Name: 3-Oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]dodecanamide

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Biological Activity

N-(3-Oxododecanoyl)-L-homoserine lactone is a bacterial quorum sensing signal molecule. Inhibits lymphocyte proliferation and TNF-α and IL-12 production by LPS-stimulated macrophages. Inhibits or promotes antibody production at high and low concentrations, respectively, in keyhole limpet hemocyanin (KLH)-stimulated spleen cells. Immunomodulator.

Technical Data

M.Wt:
297.39
Formula:
C16H27NO4
Solubility:
Soluble to 100 mM in DMSO
Storage:
Store at -20°C
CAS No:
168982-69-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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