N-(3-Oxododecanoyl)-L-homoserine lactone

Key Product Details

Product Description

N-(3-Oxododecanoyl)-L-homoserine lactone is a bacterial quorum sensing signal molecule. Inhibits lymphocyte proliferation and TNF-α and IL-12 production by LPS-stimulated macrophages. Inhibits or promotes antibody production at high and low concentrations, respectively, in keyhole limpet hemocyanin (KLH)-stimulated spleen cells. Immunomodulator.

Product Specifications

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions

The following data is based on the product molecular weight 297.39.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.36 mL	16.81 mL	33.63 mL
5 mM	0.67 mL	3.36 mL	6.73 mL
10 mM	0.34 mL	1.68 mL	3.36 mL
50 mM	0.07 mL	0.34 mL	0.67 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Telford The Pseudomonas aeruginosa quorum-sensing signal molecule N-(3-oxododecanoyl)-L-homoserine lactone has immunomodulatory activity. Infect.Immun. 1998 PMID: 9423836

Product Documents for N-(3-Oxododecanoyl)-L-homoserine lactone