NCAPD3 Antibody - BSA Free

Novus Biologicals | Catalog # NBP3-47379

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Western Blot, ELISA, Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all NCAPD3 Primary Antibodies »

Product Specifications

Immunogen

non-SMC condensin II complex, subunit D3. (Uniprot# P42695)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

165 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for NCAPD3 Antibody - BSA Free

NCAPD3 Antibody - BSA Free

Immunoprecipitation: NCAPD3 Antibody - BSA Free [NBP3-47379] -

Immunoprecipitation: NCAPD3 Antibody - BSA Free [NBP3-47379] - IP Result of anti-NCAPD3 (IP:, 4ug; Detection: 1:500) with HeLa cells lysate 600ug.
NCAPD3 Antibody - BSA Free

Western Blot: NCAPD3 Antibody - BSA Free [NBP3-47379] -

Western Blot: NCAPD3 Antibody - BSA Free [NBP3-47379] - HepG2 cells were subjected to SDS PAGE followed by western blot with (NCAPD3 antibody) at dilution of 1:800

Applications for NCAPD3 Antibody - BSA Free

Application
Recommended Usage

Immunoprecipitation

1:200-1:2000

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS, 50% Glycerol, pH (7.3)

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: NCAPD3

Smad3 is a 50 kDa member of a family of proteins that act as key mediators of TGF beta superfamily signaling in cell proliferation, differentiation and development. The Smad family is divided into three subclasses: receptor regulated Smads, activin/TGF beta receptor regulated (Smad2 and 3) or BMP receptor regulated (Smad 1, 5, and 8); the common partner, (Smad4) that functions via its interaction to the various Smads; and the inhibitory Smads, (Smad6 and 7). Activated Smad3 oligomerizes with Smad4 upon TGF beta stimulation and translocates as a complex into the nucleus, allowing its binding to DNA and transcription factors. Phosphorylation of the two TGF beta dependent serines 423 and 425 in the C terminus of Smad3 is critical for Smad3 transcriptional activity and TGF beta signaling.

Alternate Names

CAPD3, CAP-D3, FLJ42888, hCAP-D3condensin-2 complex subunit D3, hcp-6, hHCP-6, KIAA0056MGC104671, Non-SMC condensin II complex subunit D3, non-SMC condensin II complex, subunit D3

Gene Symbol

NCAPD3

Additional NCAPD3 Products

Product Documents for NCAPD3 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for NCAPD3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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