NEIL2 Antibody - BSA Free

Novus Biologicals | Catalog # NBP2-68972

Novus Biologicals
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all NEIL2 Primary Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: IHPLSLGSVLSASRREVLVDHVVEFSTAWLQGKFQGRPQHTQVYQKEQCPAGHQVMKEAFGPEDGLQRLTWWCPQCQPQLSEEPEQCQFS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NEIL2 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: NEIL2 Antibody [NBP2-68972]

Immunocytochemistry/ Immunofluorescence: NEIL2 Antibody [NBP2-68972]

Immunocytochemistry/Immunofluorescence: NEIL2 Antibody [NBP2-68972] - Staining of human cell line A549 shows localization to nucleoplasm. Antibody staining is shown in green.
NEIL2 Antibody - BSA Free Chromatin Immunoprecipitation ChIP: NEIL2 Antibody - BSA Free

Chromatin Immunoprecipitation ChIP: NEIL2 Antibody - BSA Free

ChIP-Exo-Seq composite graph for Anti-NEIL2 tested in K562 cells. Strand-specific reads (blue: forward, red: reverse) and IgG controls (black: forward, grey: reverse) are plotted against the distance from a composite set of reference binding sites. The antibody exhibits robust target enrichment compared to a non-specific IgG control and precisely reveals its structural organization around the binding site. Data generated by Prof. B. F. Pugh's Lab at Cornell University.

Applications for NEIL2 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF Fixation/Permeabilization: PFA/Triton X-100

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NEIL2

NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226])[supplied by OMIM]

Alternate Names

DNA glycosylase/AP lyase Neil2, EC 3.2.2.-, EC 4.2.99.18, endonuclease 8-like 2, Endonuclease VIII-like 2, FLJ31644, MGC2832, MGC4505, NEH2DNA-(apurinic or apyrimidinic site) lyase Neil2, nei endonuclease VIII-like 2 (E. coli), Nei homolog 2, nei like 2, nei like 2 (E. coli), NEI2, Nei-like protein 2

Gene Symbol

NEIL2

Additional NEIL2 Products

Product Documents for NEIL2 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for NEIL2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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