Induces neurogenesis of non-pluripotent C2C12 myoblasts and cells derived from mature human skeletal muscle. Upregulates the expression of neuron-specific markers in C2C12 cells.
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Synthetic small molecules that induce neurogenesis in skeletal muscle.
Williams et al.
Combining suppression of stemness with lineage-specific induction leads to conversion of pluripotent cells into functional neurons.
Halder et al.