Nitrendipine

Tocris Bioscience | Catalog # 0601

CaV1.x blocker
Tocris Bioscience
Discontinued Product
0601 has been discontinued. View all Voltage-gated Calcium Channel Blockers products.

Key Product Details

Description

CaV1.x blocker
View all Voltage-gated Calcium Channel Blockers »

Product Description

Nitrendipine is a L-type calcium channel blocker. Induces autophagy.

Product Specifications for Nitrendipine

Molecular Weight

360.37

Formula

C18H20N2O6

Storage

Store at RT

Purity

≥99% (HPLC)

Chemical Name

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridine dicarboxylic acid ethyl methyl ester

CAS Number

39562-70-4

PubChem ID

4507

InChI Key

PVHUJELLJLJGLN-UHFFFAOYSA-N

SMILES

CCOC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 50
Ethanol 25

Preparing Stock Solutions for Nitrendipine

The following data is based on the product molecular weight 360.37.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 5.55 mL 27.75 mL 55.50 mL
2.5 mM 1.11 mL 5.55 mL 11.10 mL
5 mM 0.55 mL 2.77 mL 5.55 mL
25 mM 0.11 mL 0.55 mL 1.11 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 35 publications citing the usage of this product.

Product Documents for Nitrendipine

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Nitrendipine

For research use only

Related Research Areas

Ion Channels and Regulators

Customer Reviews for Nitrendipine (1)

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  • Nitrendipine was measured against other calcium channel blockers
    Name: Anonymous
    Species: Human
    Verified Customer | Posted 02/20/2019
    Nitrendipine blocks L-type calcium channels in smooth muscle cells and its effectiveness was measured against other calcium channel blockers.
    Nitrendipine 0601

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