Catalog Number: 0601
Chemical Name: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridine dicarboxylic acid ethyl methyl ester
Biological Activity
L-type calcium channel blocker.
Technical Data
  • M.Wt:
    360.37
  • Formula:
    C18H20N2O6
  • Solubility:
    Soluble to 50 mM in DMSO and to 25 mM in ethanol
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    39562-70-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References

  1. Kishimoto T et al.
    Leucocyte Typing VI. Garland Publishing Inc. London.
  2. L-type calcium channel block by highly hydrophilic dihydropyridines in single ventricular cells of guinea-pig hearts.
    Watanabe et al.
    J.Mol.Cell.Cardiol., 1995;27:1271
  3. Characterization of a voltage-dependent L-type calcium channel from rabbit and turtle brain.
    Costa et al.
    Neurochem.Res., 1996;21:537
  4. Chemical modulators of autophagy as biological probes and potential therapeutics.
    Fleming et al.
    Nat.Chem.Biol., 2011;7:9
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Nitrendipine include:

2 Citations: Showing 1 - 2
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  1. Erk1/2 inhibit synaptic vesicle exocytosis through L-type calcium channels.
    Authors: Subramanian and Morozov
    J Neurosci 2011;31:4755
  2. Regulation of protease-activated receptor-1 by vasodilatory prostaglandins via NFAT.
    Authors: Rosenkranz Et al.
    Cardiovasc Res 2009;83:778

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