Home / Ubiquitin Conjugating Enzyme (E2) Inhibitors / NSC 697923

NSC 697923

Catalog #: 4858 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4858/10
4858/50
NSC 697923 | CAS No. 343351-67-7 | Ubiquitin Conjugating Enzyme (E2) Inhibitors
1 Image
Description: Selective UBE2N inhibitor

Chemical Name: 2-[(4-Methylphenyl)sulfonyl]-5-nitrofuran

Purity: ≥98%

Product Details
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

NSC 697923 is a selective inhibitor of the E2 ubiquitin (Ub) conjugating enzyme UBE2N (Ubc13). Inhibits UBE2N-Ub conjugation and activity of the UBE2N-Ueva1A complex. Has no effect on UbcH5c activity. Inhibits NF-κB activation in diffuse large B-cell lymphoma (DLBCL) cells. Inhibits cell growth and induces apoptosis in DLBCL and neuroblastoma (NB) cell lines. Supresses NB cell xenograft tumor growth in vivo.

Technical Data

M.Wt:
267.26
Formula:
C11H9NO5S
Solubility:
Soluble to 100 mM in DMSO and to 25 mM in ethanol with gentle warming
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
343351-67-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for NSC 697923

There are currently no reviews for this product. Be the first to review NSC 697923 and earn rewards!

Have you used NSC 697923?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.