Chemical Name: N-1H-Pyrrolo[2,3-c]pyridin-5-ylbenzamide
Biological ActivityOct4 activator. Enhances and accelerates iPSC reprogramming in the presence of 4F (Oct4, Sox2, c-Myc and Klf4) by ~20-fold compared to 4F alone. Induces mRNA expression of Oct4, Sox2 and Nanog and also Tet1. Displays no effects on p53-p21 pathway or Wnt-β-catenin signaling.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Identification of Oct4-activating compounds that enhance reprogramming efficiency.
Li et al.
No product specific FAQs exist for this product, however you mayView all Small Molecule FAQs
Reviews for OAC-1
There are currently no reviews for this product. Be the first to review OAC-1 and earn rewards!
Have you used OAC-1?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image