Catalog Number: 1142
Chemical Name: 3-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethyl-phenol hydrochloride
Biological Activity
Partial α2A adrenoceptor agonist and α1A agonist. Agonist/antagonist activity at 5-HT receptors.
Technical Data
  • M.Wt:
    296.84
  • Formula:
    C16H24N2O.HCl
  • Solubility:
    Soluble to 50 mM in water
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    2315-02-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Cardiovascular effects of oxymetazoline and UK14,304 in conscious and pithed rats.
    Bayorh et al.
    Clin.Exp.Hypertens., 1997;19:445
  2. Selectivity of the imidazoline α-adrenoceptor agonists (oxymetazoline and cirazoline) for human cloned α1-adrenoceptor subtypes.
    Horie et al.
    Br.J.Pharmacol., 1995;116:1611
  3. Interaction of the α-adrenoceptor agonist oxymetazoline with serotonin 5-HT1A, 5-HT1B, 5-HT1C and 5-HT1D receptors.
    Schoeffter et al.
    Eur.J.Pharmacol., 1991;196:213
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Oxymetazoline hydrochloride include:

1 Citations: Showing 1 - 1

  1. An Alpha-1A Adrenergic Receptor Agonist Prevents Acute Doxorubicin Cardiomyopathy in Male Mice.
    Authors: Montgomery
    Plos One 2017;12:e0168409

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