Chemical Name: (Z)-3-(4-Iodophenyl)-2-mercapto-2-propenoic acid
Biological Activity Selective, cell-permeable non-peptide calpain inhibitor (Ki values for ν and m-calpains are 0.21 and 0.37 μM respectively). Targets the calcium binding sites of calpain. Demonstrates high specificity for calpains relative to other proteases, and is a non-competitive inhibitor with respect to the substrate.
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Store at -20°C
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