pep2-SVKI

  ( 4 citations )    
Product Datasheet
Catalog Number:1597
Chemical Name:
Product Details
Citations (4)
Supplemental Products
Reviews
Biological Activity
Inhibitor peptide corresponding to last 10 amino acids of the C-terminus of the GluR2 AMPA receptor subunit. Disrupts binding of GluR2 (at the C-terminal PDZ site) with glutamate receptor interacting protein (GRIP), AMPA receptor binding protein (ABP) and protein interacting with C kinase (PICK1). Increases amplitude of AMPA receptor-mediated currents and blocks long-term depression (LTD).

Control Peptide also available.

Technical Data
  • M.Wt:
    1284.47
  • Formula:
    C60H93N13O18
  • Sequence:
    YNVYGIESVKI
  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    328944-75-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for pep2-SVKI include:

4 Citations: Showing 1 - 4
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  1. Distinct forms of Gq-receptor-dependent plasticity of excitatory transmission in the BNST are differentially affected by stress.
    Authors: McElligott Et al.
    J Neurosci  2010;107:2271
  2. Co-induction of LTP and LTD and its regulation by protein kinases and phosphatases.
    Authors: Grey and Burrell
    J Neurophysiol  2010;103:2737
  3. A novel mechanism of hippocampal LTD involving muscarinic receptor-triggered interactions between AMPARs, GRIP and liprin-alpha.
    Authors: Dickinson Et al.
    Mol Brain  2009;2:18
  4. Activity-dependent synaptic plasticity in retinal ganglion cells.
    Authors: Xia Et al.
    J Neurosci  2007;27:12221

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