Pep2m, myristoylated

Name: Pep2m, myristoylated
Brand: Tocris Bioscience
SKU: 3801

Tocris Bioscience | Catalog # 3801

Submit a review

Product Documents

Peptide inhibitor of GluA2 subunit binding to NSF; myristoylated form of pep2m (Cat. No. 1595).

Discontinued Product

3801 has been discontinued. View all AMPA Receptor Inhibitors products.

Technical Data
Reviews

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

Peptide inhibitor of GluA2 subunit binding to NSF; myristoylated form of pep2m (Cat. No. 1595).

Alternative Names

myr-pep2m

View all AMPA Receptor Inhibitors »

Product Description

Pep2m, myristoylated is a cell-permeable, myristoylated form of pep2m (Cat. No. 1595). Peptide inhibitor of the interaction between the C-terminus of the GluA2 (AMPA receptor) subunit and N-ethylmaleimide-sensitive fusion protein (NSF), a protein that regulates AMPA receptor function. Reduces postsynaptic currents in CA1 neurons, AMPA-mediated currents in cultured hippocampal neurons and AMPA receptor surface expression.

Product Specifications for Pep2m, myristoylated

Molecular Weight

1383.80

Formula

C₆₃H₁₁₈N₁₈O₁₄S

Storage

Store at -20°C

CAS Number

1423381-07-0

PubChem ID

90488880

InChI Key

WOHZPGNQJGMOFO-KJNWLHRWSA-N

SMILES

[H]N([C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(O)=O)C(=O)CCCCCCCCCCCCC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 1mg/ml in water

Calculators

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt*

g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Calculate the dilution required to prepare a stock solution.

Concentration 1 (C1)

Volume 1 (V1)

Concentration 2 (C2)

Volume 2 (V2)

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background References

References are publications that support the biological activity of the product.

Yao PKMz maintains late long-term potentiation by N-ethylmaleimide-sensitive factor/GluR2-dependent trafficking of postsynaptic AMPA receptors. J.Neurosci. 2008 PMID: 18667614
Luscher Role of AMPA receptor cycling in synaptic transmission and plasticity. Neuron 1999 PMID: 10595516
Noel Surface expression of AMPA receptors in hippocampal neurons is regulated by an NSF-dependent mechanism. Neuron 1999 PMID: 10399941
Luthi Hippocampal LTD expression involves a pool of AMPARs regulated by the NSF-GluR2 interaction. Neuron 1999 PMID: 10571232
Nishimune NSF binding to GluR2 regulates synaptic transmission. Neuron 1998 PMID: 9697854

Product Documents for Pep2m, myristoylated

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Download SDS

Product Specific Notices for Pep2m, myristoylated

For research use only

Customer Reviews for Pep2m, myristoylated

There are currently no reviews for this product. Be the first to review Pep2m, myristoylated and earn rewards!

Have you used Pep2m, myristoylated?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image