Phencyclidine hydrochloride

Key Product Details

Product Description

Phencyclidine hydrochloride is a non-competitive NMDA receptor antagonist and sigma receptor agonist. Psychostimulant; induces rotational behavior, head-weaving and cognitive dysfunction in rats.

Product Specifications for Phencyclidine hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Phencyclidine hydrochloride

The following data is based on the product molecular weight 279.85.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.4 mM	8.93 mL	44.67 mL	89.33 mL
2 mM	1.79 mL	8.93 mL	17.87 mL
4 mM	0.89 mL	4.47 mL	8.93 mL
20 mM	0.18 mL	0.89 mL	1.79 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 8 publications citing the usage of this product.

• Jin The involvement of σ receptors in the choice reaction performance deficits induced by phencyclidine. Eur.J.Pharmacol. 1997 PMID: 9042584
• Sharp Phencyclidine (PCP) acts at σ sites to induce c-fos gene expression. Brain Res. 1997 PMID: 9203533
• Linders Synthesis and binding properties of MK-801 isothiocyanates; (+)-3-isothiocyanato-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine hydrochloride: a new potent and selective electrophilic affinity ligand for the NMDA receptor-c J.Med.Chem. 1993 PMID: 8355251

Product Documents for Phencyclidine hydrochloride