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PHM 27 (human)

2080 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
2080/1
PHM 27 (human)
1 Image
Description: Potent calcitonin agonist; endogenous analog of human VIP
Alternative Names: Peptide histidine methionine 27 (human), Human PHI 27
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Biological Activity

PHM 27 (human) is an endogenous peptide product of human prepro-VIP and analog of porcine PHI-27; potent agonist for the human calcitonin receptor (EC50 = 11 nM). Transgenic mice expressing the human VIP/PHM 27 gene in pancreatic β-islets display enhanced glucose-induced insulin secretion.

Technical Data

M.Wt:
2985.44
Formula:
C135H214N34O40S
Sequence:
HADGVFTSDFSKLLGQLSAKKYLESLM

(Modifications: Met-27 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in 5% acetonitrile / water
Storage:
Desiccate at -20°C
CAS No:
87403-73-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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VersaClone cDNA Plasmids

Human Calcitonin R (NP_001733) VersaClone cDNA

RDC0108

Mouse Calcitonin R (NP_031614) VersaClone cDNA

RDC0206

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