PHM 27 (human)
Biological Activity
Endogenous peptide product of human prepro-VIP and analog of porcine PHI-27; potent agonist for the human calcitonin receptor (EC50 = 11 nM). Transgenic mice expressing the human VIP/PHM 27 gene in pancreatic β-islets display enhanced glucose-induced insulin secretion.Technical Data
(Modifications: Met-27 = C-terminal amide)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Human preprovasoactive intestinal polypeptide contains a novel PHI-27-like peptide, PHM-27.
Itoh et al.
Nature, 1983;304:547 -
Transgenic mice overexpressing human vasoactive intestinal peptide (VIP) gene in pancreatic β cells.
Kato et al.
J.Biol.Chem., 1994;269:21223 -
Discovery of novel peptide/receptor interactions: identification of PHM-27 as a potent agonist of the human calcitonin receptor.
Ma et al.
Biochem.Pharmacol., 2004;67:1279
Product Datasheets
Reconstitution Calculator
Molarity Calculator
FAQs
No product specific FAQs exist for this product, however you may
View all Peptide FAQsVersaClone cDNA Plasmids
Reviews for PHM 27 (human)
There are currently no reviews for this product. Be the first to review PHM 27 (human) and earn rewards!
Have you used PHM 27 (human)?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image