Pimozide

Tocris Bioscience | Catalog # 0937

D2-like antagonist; also high affinity 5-HT7 antagonist
Tocris Bioscience
Discontinued Product
0937 has been discontinued. View all Non-selective Dopamine Receptor Antagonists products.

Key Product Details

Description

D2-like antagonist; also high affinity 5-HT7 antagonist
View all Non-selective Dopamine Receptor Antagonists »

Product Description

Pimozide is a dopamine D2-receptor antagonist and antipsychotic which binds with very high affinity to the cloned rat 5-HT7 receptor (Ki = 0.5 nM).

Product Specifications for Pimozide

Molecular Weight

461.55

Formula

C28H29F2N3O

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

1-[1-[4,4-Bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one

CAS Number

2062-78-4

PubChem ID

16362

InChI Key

YVUQSNJEYSNKRX-UHFFFAOYSA-N

SMILES

FC1=CC=C(C=C1)C(CCCN1CCC(CC1)N1C(=O)NC2=CC=CC=C12)C1=CC=C(F)C=C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 9.23 20

Preparing Stock Solutions for Pimozide

The following data is based on the product molecular weight 461.55.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 10.83 mL 54.17 mL 108.33 mL
1 mM 2.17 mL 10.83 mL 21.67 mL
2 mM 1.08 mL 5.42 mL 10.83 mL
10 mM 0.22 mL 1.08 mL 2.17 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 31 publications citing the usage of this product.

Product Documents for Pimozide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Pimozide

For research use only

⚠ WARNING: This product can expose you to chemicals including Pimozide, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

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