PNU 177864 hydrochloride

Key Product Details

Product Description

PNU 177864 hydrochloride is a highly selective dopamine D₃ receptor antagonist. Induces phospholipidosis and exhibits antischizophrenic activity in vivo.

Product Specifications for PNU 177864 hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for PNU 177864 hydrochloride

The following data is based on the product molecular weight 438.89.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.28 mL	11.39 mL	22.78 mL
5 mM	0.46 mL	2.28 mL	4.56 mL
10 mM	0.23 mL	1.14 mL	2.28 mL
50 mM	0.05 mL	0.23 mL	0.46 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Rudmann Epididymal and systemic phospholipidosis in rats and dogs treated with DA D3 selective antagonist PNU-177864. Toxicol.Pathol. 2004 PMID: 15204974
• Vonderfecht Myopathy related to administration of a cationic amphiphilic drug and the use of multidose drug distribution analysis to predict its occurrence. Toxicol.Pathol. 2004 PMID: 15204973

Product Documents for PNU 177864 hydrochloride