PRIMA-1MET

Catalog # Availability Size / Price Qty
3710/10
PRIMA-1MET | CAS No. 5291-32-7 | Additional p53-related Compounds
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Description: Restores mutant p53 activity
Alternative Names: APR-246

Chemical Name: 2-(Hydroxymethyl)-2-(methoxymethyl)-1-azabicyclo[2.2.2]octan-3-one

Purity: ≥98%

Product Details
Citations (1)
Reviews

Biological Activity

Methylated derivative of PRIMA-1 (Cat. No. 1862). Restores mutant activity p53 activity. Acts synergistically with chemotherapeutic agents to inhibit tumor cell proliferation.

Technical Data

M.Wt:
199.25
Formula:
C10H17NO3
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
5291-32-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for PRIMA-1MET

The citations listed below are publications that use Tocris products. Selected citations for PRIMA-1MET include:

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