PRIMA-1

Catalog # Availability Size / Price Qty
1862/10
1862/50
PRIMA-1 | CAS No. 5608-24-2 | Additional p53-related Compounds
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Description: Restores mutant p53 activity; induces apoptosis

Chemical Name: 2,2-Bis(hydroxymethyl)-1-azabicyclo[2.2.2]octan-3-one

Purity: ≥99%

Product Details
Citations (3)
Reviews

Biological Activity

Selectively restores mutant p53 activity in tumor cells via activation of Bax and PUMA. Induces apoptosis and inhibits growth of tumors with mutant p53.

Technical Data

M.Wt:
185.22
Formula:
C9H15NO3
Solubility:
Soluble to 100 mM in water
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
5608-24-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for PRIMA-1

The citations listed below are publications that use Tocris products. Selected citations for PRIMA-1 include:

3 Citations: Showing 1 - 3

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