Recombinant T. gondii Profilin Protein

Name: Recombinant T. gondii Profilin Protein
Brand: Novus Biologicals
SKU: NBP3-18156
Price: 269 USD
Availability: InStock

Novus Biologicals | Catalog # NBP3-18156

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Product Specifications
Preparation & Storage
Calculators
Background
Product Documents
Specific Notices

Key Product Details

Source

E. coli

Accession Number

Q58NA1

Applications

SDS-PAGE

View all Profilin Proteins and Enzymes »

Product Specifications

Description

Recombinant profilin (Toxoplasma gondii) (aa 1-163).

Source: E. coli

Uniprot ID: Q58NA1

Purity

>95% pure by SDS-PAGE

Endotoxin Level

<0.01EU/ug purified protein (LAL test; Lonza).

Predicted Molecular Mass

20 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Protein / Peptide Type

Recombinant Protein

Formulation, Preparation, and Storage

NBP3-18156

Formulation	Lyophilized from PBS
Preservative	No Preservative
Concentration	Lyoph
Reconstitution	Reconstitute with 100 ul sterile water (0.1mg/ml after reconstitution)
Shipping	The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Volume (to add to vial)

Mass (in vial)

Desired Reconstitution Concentration

Background: Profilin

TLR11, an innate sensor for profilin (Toxoplasma gondii), is an intracellular receptor that resides in the endoplasmic reticulum. The 12 membrane-spanning endoplasmic reticulum-resident protein UNC93B1 interacts directly with TLR11 and regulates the activation of dendritic cells in response to profilin (Toxoplasma gondii) and parasitic infection in vivo. TLR12, a previously uncharacterized TLR, also recognizes profilin from Toxoplasma gondii. TLR12 is sufficient for recognition of profilin by plasmacytoid dendritic cells (pDCs), whereas TLR11 and TLR12 are both required in macrophages and conventional DCs. In contrast to TLR11, TLR12-deficient mice succumb rapidly to T. gondii infection.

Alternate Names

PRF

UniProt

Q58NA1 (T. gondii)

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Product Documents for Recombinant T. gondii Profilin Protein

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Product Specific Notices for Recombinant T. gondii Profilin Protein

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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