Proteome Purify 2 Mouse Serum Protein Immunodepletion Resin

Catalog # Availability Size / Price Qty
MIDR002-020
MIDR002-040
Product Details
Citations (2)
FAQs
Supplemental Products
Reviews (2)

Proteome Purify 2 Mouse Serum Protein Immunodepletion Resin Summary

The wide dynamic range of protein concentrations present in serum and plasma represents a major challenge for the analysis of the proteome. The range of plasma protein concentrations, from low abundance proteins such as cytokines (pg/mL) to albumin (30-45 mg/mL), represents at least 10 orders of magnitude. Analysis of low abundance proteins by even the most sensitive of methods for proteomics greatly benefits from the removal of high abundance proteins that may interfere with their detection.

The Proteome Purify™ 2 Mouse Serum Protein Immunodepletion Resin is a single-use resin that depletes serum or plasma of albumin and IgG. The two proteins removed by this kit represent approximately 60% of the protein contained in serum and plasma.

Features

  • Depletes serum of albumin and IgG
  • Improves visualization of target proteins
  • Allows user to increase protein load or concentration

Kit Contents

  • Immunodepletion Resin
  • 4 Spin-X Filter Units

Specifications

Shipping Conditions
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Species
Mouse

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Citations for Proteome Purify 2 Mouse Serum Protein Immunodepletion Resin

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. A Soluble Platelet-Derived Growth Factor Receptor-beta Originates via Pre-mRNA Splicing in the Healthy Brain and is Differentially Regulated during Hypoxia and Aging
    Authors: LB Payne, H Abdelazim, M Hoque, A Barnes, Z Mironovova, CE Willi, J Darden, C Jenkins-Ho, MW Sedovy, SR Johnstone, JC Chappell
    bioRxiv : the preprint server for biology, 2023-02-04;0(0):.  2023-02-04
  2. Hemoadsorption Improves Survival of Rats Exposed to an Acutely Lethal Dose of Aflatoxin B1
    Authors: KG Ruggeberg, P O'Sullivan, TJ Kovacs, K Dawson, VJ Capponi, PP Chan, TD Golobish, MC Gruda
    Sci Rep, 2020-01-21;10(1):799.  2020-01-21

FAQs

  1. Does the Mouse Serum Protein Immunodepletion Resin, Catalog # MIDR002, contain any detergents in the Resin slurry?  

    • No. The Mouse Serum Protein Immunodepletion Resin does not contain any detergents in the Resin slurry.  As described in the product insert, the resin is suspended in PBS with 0.02% sodium azide (pH 7.4).

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Reviews for Proteome Purify 2 Mouse Serum Protein Immunodepletion Resin

Average Rating: 5 (Based on 2 Reviews)

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Proteome Purify 2 Mouse Serum Protein Immunodepletion Resin
By Anonymous on 05/13/2021

Proteome Purify 2 Mouse Serum Protein Immunodepletion Resin
By Anonymous on 03/20/2019

Easy to use, works perfectly as described. Was able to see the desired bands after immunodepletion