Key Product Details

Species Reactivity

Human, Rat

Applications

Western Blot, ELISA

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all PRTFDC1 Primary Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 14 amino acid synthetic peptide from near the center of human PRTFDC1. The immunogen is located within amino acids 90 - 140 of PRTFDC1. Amino Acid Squence: MKVDFIRLKSYRND

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Chicken (86%), Porcine (86%), Bovine (86%), Mouse (86%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PRTFDC1 Antibody - BSA Free

Western Blot: PRTFDC1 AntibodyBSA Free [NBP1-76358]

Western Blot: PRTFDC1 AntibodyBSA Free [NBP1-76358]

Western Blot: PRTFDC1 Antibody [NBP1-76358] - Human brain tissue lysate with PRTFDC1 antibody at 1 ug/mL in the (A) absence and (B) presence of blocking peptide.

Applications for PRTFDC1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PRTFDC1

Phosphoribosyl transferase domain containing 1 (PRTFDC1) is highly homologous to the hypoxanthine phosphoribosyltransferase (HPRT1) and may have arisen from a gene duplication event of a common ancestor gene. Recently, it was shown that CpG islands in the PRTFDC1 promoter could be hypermethylated in ovarian cancers and oral squamous-cell carcinomas (OSCC), leading to gene silencing. Restoration of PRTFDC1 expression in OSCC inhibited cell growth in colony-formation assays, while knockdown of PRTFDC1 expression in OSCC that expressed the gene promoted cell growth. These results suggest that PRTFDC1 can act as a tumor-suppressor gene. At least three isoforms of PRTFDC1 are known to exist.

Alternate Names

EC 2.4.2.8, FLJ11888, HHGPEC 2.4.2, phosphoribosyl transferase domain containing 1, phosphoribosyltransferase domain-containing protein 1

Gene Symbol

PRTFDC1

UniProt

NP_064585 (Human)

Additional PRTFDC1 Products

Product Documents for PRTFDC1 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for PRTFDC1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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